Journal: BioMed Research International

Article Title: A High-Fat Diet Exacerbates the Course of Experimental Trypanosoma cruzi Infection That Can Be Mitigated by Treatment with Simvastatin

doi: 10.1155/2020/1230461

Figure Lengend Snippet: Trypanosoma cruzi increases total cholesterol, LDL, and triglycerides during acute phase of experimental infection. C5BL/6 mice were infected with VL-10 of T. cruzi and plasma used to measure total cholesterol (a), HDL cholesterol (b), LDL cholesterol (c), and triglycerides (d) using colorimetric enzymatic kits. Animals were fed with normolipid or high-fat diets and treated or not with simvastatin. White bars: uninfected animals; black bars: animals infected with T. cruzi . The data are mean ± standard error of the mean (SEM).

Article Snippet: The total cholesterol, HDL, and triglycerides were determined in plasma samples, using an enzymatic colorimetric kit for cholesterol, triglycerides, and HDL liquiform, from Labtest Diagnostica SA (Lagoa Santa, MG, BR).

Techniques: Infection, Clinical Proteomics